CAS No. 512-06-1
Batch:
Purity:97
Chemical Structure
Check the
Yamogenin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 512-06-1 | |
|---|---|---|
| Molecular Formula |
C27H42O3 |
|
| Molecular Weight (MW) | 414.62 | |
| SMILES | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1 |
Yamogenin is a natural steroidal sapogenin derived from fenugreek that acts as an inhibitor of hepatic lipid accumulation. It suppresses the expression of genes involved in fatty acid synthesis within hepatocytes, downregulating lipogenic pathways. This inhibition reduces intracellular triglyceride storage and attenuates hepatic lipid buildup, serving as a key regulator of metabolic signaling and lipid homeostasis in liver cells.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 8 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.