XAV-939 is a specific tankyrase inhibitor. It affects the Wnt/β-catenin signaling pathway by stabilizing Axin and promoting β-catenin degradation, effectively inhibiting tumor cell proliferation, migration, and chemoresistance, while modulating stem cell differentiation.
XAV-939 Mechanism of Action: Tankyrase Inhibition in Cancer Cell Research
XAV-939 MOA：Targeting Tankyrase/Wnt/β-catenin Pathway for Cancer Biology and Oncology