CAS No. 2009-24-7

Batch: Purity:99.86
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Xanthotoxol Chemical Structure
Chemical Structure
Check the Xanthotoxol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 2009-24-7
Molecular Formula

C11H6O4
Molecular Weight (MW) 202.16
SMILES C1=CC(=O)OC2=C(C3=C(C=CO3)C=C21)O

Biological Activity

Xanthotoxol is a biologically active linear furocoumarin that acts as a 5-HT receptor antagonist and exhibits anti-inflammatory, antioxidant, and neuroprotective properties. It modulates NF-kB and MAPK signaling pathways, attenuating downstream inflammatory mediator expression and reducing cellular oxidative stress. Through these targeted pathway interactions, xanthotoxol promotes neuroprotection and mitigates cellular damage in biological models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 40 mg/mL (197.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
Water ˂1 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.