CAS No. 748146-89-6

Batch: Purity:99.80
WAY-383487 Chemical Structure
Chemical Structure
Check the WAY-383487 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-[1-[2-(4-fluoroanilino)-2-oxoethyl]cyclohexyl]acetic acid
CAS Number 748146-89-6
Molecular Formula

C16H20FNO3

Molecular Weight (MW) 293.33
SMILES OC(=O)CC1(CCCCC1)CC(=O)NC2=CC=C(F)C=C2
InChIKey NWYDUMKUVBYKQI-UHFFFAOYSA-N

Ordering Information

Biological Activity

WAY-is a Tat peptide derivative that acts as an inhibitor of HIV-1 long terminal repeat (LTR)-activated transcription. By targeting Tat-mediated transactivation, it suppresses promoter activity and downregulates downstream viral gene expression regulated by the LTR promoter complex. This inhibition disrupts viral transcriptional pathways, resulting in reduced HIV-1 transcription and attenuated viral replication in infected cells.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 59 mg/mL (201.13 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 59 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.