CAS No. 737818-56-3
Batch:
Purity:99.79
Chemical Structure
Check the
WAY-340935
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[(4-bromophenyl)methoxy]quinazoline | |
|---|---|---|
| CAS Number | 737818-56-3 | |
| Molecular Formula |
C15H11BrN2O |
|
| Molecular Weight (MW) | 315.16 | |
| SMILES | BrC1=CC=C(COC2=C3C=CC=CC3=NC=N2)C=C1 | |
| InChIKey | DADJIQURPZZXBT-UHFFFAOYSA-N |
WAY-340935 is a quinazoline derivative that acts as a synthetic vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor. By inhibiting VEGFR2 kinase activity, the compound blocks the VEGF signaling pathway and its downstream signaling cascades. This targeted pathway suppression impairs endothelial cell function and produces antiproliferative activity against the H460 non-small cell lung cancer cell line. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
63 mg/mL
(199.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.