CAS No. 491839-65-7
Batch:
Purity:99.69
Chemical Structure
Check the
WAY-320461
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-(4-bromophenyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone | |
|---|---|---|
| CAS Number | 491839-65-7 | |
| Molecular Formula | ||
| SMILES | BrC1=CC=C(C=C1)C(=O)CSC2=NN=C(O2)C3=CC=NC=C3 | |
| InChIKey | RZRDLDDOZNGXJT-UHFFFAOYSA-N |
WAY-320461 is a small-molecule inhibitor targeting focal adhesion kinase (FAK). Attenuating FAK catalytic activity impairs integrin-mediated cellular adhesion and focal adhesion complex turnover at the cell membrane. This targeted inhibition disrupts key downstream signaling cascades, including Src/ERK and PI3K/AKT pathways, ultimately suppressing cell motility, migration, invasion, and proliferation across biological models.[1][2]
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
75 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.