CAS No. 868359-05-1
Batch:
Purity:99.89
Chemical Structure
Check the
WAY-213613
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid | |
|---|---|---|
| CAS Number | 868359-05-1 | |
| Molecular Formula |
C16H13BrF2N2O4 |
|
| Molecular Weight (MW) | 415.19 | |
| SMILES | NC(CC(=O)NC1=CC=C(OC2=C(Br)C=C(F)C(=C2)F)C=C1)C(O)=O | |
| InChIKey | BNYDDAAZMBUFRG-ZDUSSCGKSA-N |
WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of excitatory amino acid transporter subtype 2 (EAAT2) with an IC50 of 85 nM. By selectively blocking EAAT2-mediated glutamate uptake without acting as a transportable substrate, WAY-213613 elevates extracellular glutamate levels, altering glutamatergic signaling and downstream synaptic excitability within central nervous system neural pathways.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(199.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.