CAS No. 440122-66-7
Batch:
Purity:99.98
Chemical Structure
Check the
WAY-200070
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 440122-66-7 | |
|---|---|---|
| Molecular Formula |
C13H8BrNO3 |
|
| Molecular Weight (MW) | 306.11 | |
| SMILES | C1=CC(=CC=C1C2=NC3=C(O2)C(=CC(=C3)O)Br)O |
WAY-200070 is a potent and selective agonist of estrogen receptor β (ERβ). By selectively activating ERβ signaling pathways, it modulates downstream gene transcription and central neurochemical activity while avoiding classic ERα-mediated tissue proliferation. In preclinical animal studies, WAY-200070 exhibits distinct central nervous system functional phenotypes, producing significant anxiolytic-like and antidepressant-like behavioral effects in rodent models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
61 mg/mL
(199.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.