Warfarin

Catalog No.S4545 Synonyms: Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin

For research use only.

Warfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.

Warfarin Chemical Structure

CAS No. 81-81-2

Purity & Quality Control

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Biological Activity

Description Warfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.

Protocol (from reference)

Chemical Information

Molecular Weight 308.33
Formula

C19H16O4

CAS No. 81-81-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03520868 Completed Diagnostic Test: Monitoring Anti Factor Xa level Atrial Fibrillation Steward St. Elizabeth''s Medical Center of Boston Inc. May 5 2017 --
NCT01391091 Completed Procedure: Radiofrequency catheter ablation Migraine|Atrial Fibrillation Texas Cardiac Arrhythmia Research Foundation December 2010 Phase 3
NCT00863382 Withdrawn Device: Standard Event Monitor|Device: Sleuth Monitor Atrial Fibrillation Dhanunjaya Lakkireddy MD FACC|University of Kansas Medical Center January 2009 Not Applicable
NCT00564356 Unknown status Procedure: cataract surgery with phacoemulsification Efficacy|Complications Sheba Medical Center July 2007 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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