2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Deutivacaftor (VX-561, Ivacaftor-D9)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-[2-tert-butyl-4-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-5-hydroxyphenyl]-4-oxo-1H-quinoline-3-carboxamide | |
|---|---|---|
| CAS Number | 1413431-07-8 | |
| Molecular Formula |
C24H19D9N2O3 |
|
| Molecular Weight (MW) | 401.55 | |
| InChIKey | PURKAOJPTOLRMP-ASMGOKTBSA-N |
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(199.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Jump to
- Deutivacaftor (VX-561, Ivacaftor-D9) Clinical Trials
- Deutivacaftor (VX-561, Ivacaftor-D9) Solubility in DMSO
- Deutivacaftor (VX-561, Ivacaftor-D9) Stock Solution
- Deutivacaftor (VX-561, Ivacaftor-D9) Storage
- Deutivacaftor (VX-561, Ivacaftor-D9) Stability
- Deutivacaftor (VX-561, Ivacaftor-D9) Molecular Weight
- Deutivacaftor (VX-561, Ivacaftor-D9) CAS Number
- Deutivacaftor (VX-561, Ivacaftor-D9) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.