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VU 0240551

Cat.No.E7694

VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. This compound also inhibits hERG and L-type Ca2+ channels. It attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission.
VU 0240551 Chemical Structure

Chemical Structure

Molecular Weight: 342.44

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Chemical Information, Storage & Stability

Molecular Weight 342.44 Formula Storage (From the date of receipt)
CAS No. 893990-34-6 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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