CAS No. 42971-09-5

Batch: Purity:99.97
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Vinpocetine Chemical Structure
Chemical Structure
Check the Vinpocetine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
CAS Number 42971-09-5
Molecular Formula

C22H26N2O2
Molecular Weight (MW) 350.45
SMILES CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC
InChIKey DDNCQMVWWZOMLN-IRLDBZIGSA-N

Ordering Information

Biological Activity

Vinpocetine is a selective inhibitor of voltage-sensitive sodium channels and phosphodiesterase 1. It directly targets IKK to suppress NF-kB pathway activation and reduce pro-inflammatory cytokine production. Additionally, blockade of voltage-gated sodium channels attenuates neuronal hyperexcitability and toxic intracellular calcium accumulation, conferring marked neuroprotective and anti-inflammatory activity in neuronal and glial cell models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 9 mg/mL (25.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.