CAS No. 4880-88-0

Batch: Purity:99.65
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Vinburnine Chemical Structure
Chemical Structure
Check the Vinburnine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 4880-88-0
Molecular Formula

C19H22N2O
Molecular Weight (MW) 294.39
SMILES CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2

Biological Activity

Vinburnine ((-)-eburnamonine) is a vinca alkaloid, metabolite of vincamine, and vasodilator that modulates cerebral blood flow and neuronal energy metabolism. By improving microvascular circulation and cellular oxygen uptake, it enhances cerebral glucose utilization and protects central nervous system tissues against hypoxic and ischemic injury, thereby supporting neuronal viability under metabolic stress conditions.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
5%TFA 6.04 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.