CAS No. 503070-58-4

Batch: Purity:99.73
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Vilanterol Trifenate Chemical Structure
Chemical Structure
Check the Vilanterol Trifenate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;2,2,2-triphenylacetic acid
CAS Number 503070-58-4
Molecular Formula

C24H33Cl2NO5.C20H16O2
Molecular Weight (MW) 774.77
SMILES OCC1=CC(=CC=C1O)C(O)CNCCCCCCOCCOCC2=C(Cl)C=CC=C2Cl.OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
InChIKey KLOLZALDXGTNQE-JIDHJSLPSA-N

Ordering Information

Biological Activity

Vilanterol trifenatate (GW642444M) is a potent, inhaled long-acting beta2 adrenoceptor agonist designed for once-daily administration. Activation of beta2 adrenoceptors leads to intracellular cAMP elevation, promoting airway smooth muscle relaxation and inhibition of bronchoconstriction. This compound exhibits prolonged bronchodilatory activity with inherent 24-hour action, supporting its utility in chronic obstructive pulmonary disease and asthma research.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (129.07 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 14 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.