CAS No. 11000-17-2
Batch:
Purity:98.56
Chemical Structure
Check the
Vasopressin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 11000-17-2 | |
|---|---|---|
| Molecular Formula | ||
| Molecular Weight (MW) | 1084.23 |
Biological Activity
Vasopressin is an endogenous neuropeptide that regulates endocrine function by acting as an agonist at vasopressin V1b receptors. In anterior pituitary corticotropes, vasopressin potentiates corticotropin-releasing hormone signaling via calcium–phospholipid pathway activation, which promotes adrenocorticotropic hormone secretion. Through these receptor-mediated interactions, vasopressin serves as a key physiological regulator of hypothalamic-pituitary-adrenal axis responses and maintains corticotroph responsiveness during chronic stress.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(92.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.