Molecular Weight: 284.18 g/mol

Varenicline (CP 526555) dihydrochloride Chemical Structure
Chemical Structure
Check the Varenicline (CP 526555) dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 57 mg/mL (200.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 57 mg/mL
Ethanol 29 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene;dihydrochloride
CAS Number 866823-63-4
Molecular Formula

C13H15Cl2N3
Molecular Weight (MW) 284.18
SMILES C1C2CNCC1C3=CC4=NC=CN=C4C=C23.Cl.Cl
InChIKey NZVVYNGXLGJKCW-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.