SMILES:

IC1=CC=CC(=C1)/C=N/NC2=NC(=NC(=N2)N(C3=CC=CC=C3)C4=CC=CC=C4)N5CCOCC5
Vacuolin-1 Chemical Structure
Chemical Structure
Check the Vacuolin-1 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-N-[(E)-(3-iodophenyl)methylideneamino]-6-morpholin-4-yl-4-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine
CAS Number 351986-85-1
Molecular Formula

C26H24IN7O
Molecular Weight (MW) 577.42
SMILES IC1=CC=CC(=C1)/C=N/NC2=NC(=NC(=N2)N(C3=CC=CC=C3)C4=CC=CC=C4)N5CCOCC5
InChIKey JMEJTSRAQUFNOP-TURZUDJPSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 10 mg/mL (17.31 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.