🎯 check Vactosertib (TEW-7197) product page
Vactosertib (TEW-7197) is a potent, orally available TGF-β RI/ALK5 inhibitor. It affects TGF-β/Smad signaling by blocking ALK5 kinase activity and Smad2/3 phosphorylation, effectively inhibiting fibrosis, epithelial-mesenchymal transition, and tumor progression.