CAS No. 545-46-0

Batch: Purity:99.85
Uvaol Chemical Structure
Chemical Structure
Check the Uvaol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 545-46-0
Molecular Formula

C30H50O2

Molecular Weight (MW) 442.72
SMILES CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)CO

Ordering Information

Biological Activity

Uvaol is a natural pentacyclic triterpene found in olive pomace oil that exhibits significant anti-inflammatory, antioxidant, and antiproliferative activities. It modulates inflammatory responses by inhibiting pro-inflammatory cytokine secretion and scavenging reactive oxygen species. Furthermore, uvaol induces cell cycle arrest and triggers apoptotic pathways in human cancer cell lines, contributing to its potential chemopreventive profile.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 3 mg/mL (6.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.