CAS No. 58-97-9

Batch: Purity:98
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Uridine 5'-monophosphate Chemical Structure
Chemical Structure
Check the Uridine 5'-monophosphate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
CAS Number 58-97-9
Molecular Formula

C9H13N2O9P
Molecular Weight (MW) 324.18
SMILES C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
InChIKey DJJCXFVJDGTHFX-XVFCMESISA-N

Biological Activity

Uridine 5'-monophosphate (5'-UMP) is an essential pyrimidine nucleotide that functions as a fundamental monomer in RNA synthesis and an intermediate in pyrimidine metabolism. It serves as a precursor for downstream pyrimidine nucleotides, including UTP and CTP, participating in the de novo and salvage pathways of nucleic acid biosynthesis. Through conversion into nucleotide derivatives, 5'-UMP supports cellular energy metabolism, phospholipid biosynthesis, and pyrimidinergic signaling cascades involved in cellular homeostasis. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO 65 mg/mL (200.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Cell. Mol. Life Sci. 2006;63(14):1575-1578.

[2] EvansDR, et al. Journal of Biological Chemistry. 2004;279(32):33035-33038.

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Note: Technical data last updated: Sep 1, 2026.