2D Structure
loading...
2D chemical structural formula diagram.
3D Structure
loading...
This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
ABT-494 (Upadacitinib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3S,4R)-3-ethyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide | |
|---|---|---|
| CAS Number | 1310726-60-3 | |
| Molecular Formula |
C17H19F3N6O |
|
| Molecular Weight (MW) | 380.37 | |
| SMILES | CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F | |
| InChIKey | WYQFJHHDOKWSHR-MNOVXSKESA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
76 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 76 mg/mL |
| Water | Insoluble |
| DMSO |
76 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 76 mg/mL |
| Water | Insoluble |
| DMSO |
76 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 76 mg/mL |
| Water | Insoluble |
| DMSO |
76 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 19 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- ABT-494 (Upadacitinib) Mechanism of Action: JAK1 Inhibition in Immune Cell Research
- ABT-494 (Upadacitinib) Clinical Trials
- ABT-494 (Upadacitinib): Selectivity & Specificity
- ABT-494 (Upadacitinib) Working Concentration | Cell Culture | Treatment
- ABT-494 (Upadacitinib) Solubility in DMSO
- ABT-494 (Upadacitinib) Stock Solution
- ABT-494 (Upadacitinib) Storage
- ABT-494 (Upadacitinib) Stability
- ABT-494 (Upadacitinib) Combination Database
- ABT-494 (Upadacitinib) Molecular Weight
- ABT-494 (Upadacitinib) SMILES
- ABT-494 (Upadacitinib) CAS Number
- ABT-494 (Upadacitinib) IC50 for Cell-based and Cell-free Assays
- ABT-494 (Upadacitinib) MedChemExpress (HY-19569)? Try a better option.
- ABT-494 (Upadacitinib) Sigma (AMBH303C4B83)? Try a better option.
- ABT-494 (Upadacitinib) Cayman (29706)? Try a better option.
- ABT-494 (Upadacitinib) Abmole (M6297)? Try a better option.
- ABT-494 (Upadacitinib) Tocris (7783)? Try a better option.
- ABT-494 (Upadacitinib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.