CAS No. 1310422-41-3
Batch:
Purity:99.86
Chemical Structure
Check the
Ulotaront hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1310422-41-3 | |
|---|---|---|
| Molecular Formula |
C9H13NOS.ClH |
|
| Molecular Weight (MW) | 219.73 |
Ulotaront hydrochloride is an orally active, CNS-penetrant psychotropic agent that acts as an agonist of trace amine-associated receptor 1 (TAAR1) and serotonin 5-HT1A receptor. Engagement of TAAR1 stimulates Gαs signaling and activates G-protein inwardly rectifying potassium (GIRK) channels. Downstream, this signaling pathway modulates monoaminergic neurotransmission, suppressing rapid eye movement sleep and attenuating phencyclidine-induced hyperactivity and sensorimotor gating deficits. [1][2]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
44 mg/mL
(200.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 44 mg/mL |
| Ethanol | 11 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.