CAS No. 51-67-2
Batch:
Purity:99.98
Chemical Structure
Check the
Tyramine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 4-(2-aminoethyl)phenol | |
|---|---|---|
| CAS Number | 51-67-2 | |
| Molecular Formula |
C8H11NO |
|
| Molecular Weight (MW) | 137.18 | |
| SMILES | C1=CC(=CC=C1CCN)O | |
| InChIKey | DZGWFCGJZKJUFP-UHFFFAOYSA-N |
Biological Activity
Tyramine is a naturally occurring trace amine derived from L-tyrosine that functions as an agonist of trace amine-associated receptor 1 (TAAR1) and acts as a sympathomimetic catecholamine-releasing agent. Upon cellular uptake, tyramine stimulates the release of monoamine neurotransmitters, including norepinephrine and dopamine, from presynaptic storage vesicles. This neurotransmitter efflux modulates monoaminergic signaling pathways to influence vascular tone, neurotransmission, and cardiovascular responses.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
27 mg/mL
(196.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 27 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.