SMILES:

O=C1NC2=C(S1)C(C3C4CC(C3S2)C5C4C(=O)N(C5=O)C6=CC=CC=C6)C7=CC=CC=C7
TSHR antagonist S37 Chemical Structure
Chemical Structure
Check the TSHR antagonist S37 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1217616-61-9
Molecular Formula

C25H20N2O3S2
Molecular Weight (MW) 460.57
SMILES O=C1NC2=C(S1)C(C3C4CC(C3S2)C5C4C(=O)N(C5=O)C6=CC=CC=C6)C7=CC=CC=C7

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 92 mg/mL (199.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.