CAS No. 1508-75-4
Batch:
Purity:100.00
Chemical Structure
Check the
Tropicamide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1508-75-4 | |
|---|---|---|
| Molecular Formula |
C17H20N2O2 |
|
| Molecular Weight (MW) | 284.35 | |
| SMILES | CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2 |
Tropicamide is an anticholinergic compound and a muscarinic receptor subtype M4-preferring antagonist (IC50 of 8.0 nM). By selectively blocking muscarinic receptors, tropicamide inhibits G protein-coupled signaling cascades downstream of acetylcholine activation. This disruption of cholinergic neurotransmission modulates intracellular cyclic AMP levels and calcium signaling, resulting in relaxed smooth muscle and altered neuronal excitability. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
57 mg/mL
(200.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 57 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.