CAS No. 9036-19-5

Triton X-114 Chemical Structure
Chemical Structure
Check the Triton X-114 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 9036-19-5
Molecular Formula

(C2H4O)nC14H22O

Biological Activity

Triton X-114 is a nonionic detergent used to solubilize cellular membranes and partition amphiphilic targets. Above its clouding temperature, it undergoes reversible phase separation into distinct aqueous and detergent-rich phases. Hydrophilic proteins partition into the aqueous phase, whereas hydrophobic integral membrane proteins partition into the detergent phase, facilitating the functional separation and isolation of membrane-associated complexes. [1]

Solubility

Reference

[1] Bordier C. J Biol Chem. 1981;256(4):1604-7.

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Note: Technical data last updated: Sep 1, 2026.