CAS No. 510758-28-8

Batch: Purity:99.71
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Tris(benzyltriazolylmethyl)amine Chemical Structure
Chemical Structure
Check the Tris(benzyltriazolylmethyl)amine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 510758-28-8
Molecular Formula

C30H30N10
Molecular Weight (MW) 530.63

Ordering Information

Biological Activity

Tris(benzyltriazolylmethyl)amine (TBTA) is a stabilizing tertiary amine ligand for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. By coordinating and stabilizing the active copper(I) oxidation state, TBTA effectively prevents oxidation and dramatically accelerates bioorthogonal click chemistry reactions with nonchelating azides. This enhancement enables efficient site-specific conjugation and biochemical labeling of biomolecules, including proteins, nucleic acids, and enzymes, in complex biological systems. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (188.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 3 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.