CAS No. 554-92-7
Batch:
Purity:99.96
Chemical Structure
Check the
Tribenzagan Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 554-92-7 | |
|---|---|---|
| Molecular Formula |
C21H28N2O5.HCl |
|
| Molecular Weight (MW) | 424.92 | |
| SMILES | CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC.Cl |
Tribenzagan Hydrochloride (Trimethobenzamide) is an orally active antiemetic agent that acts as a receptor antagonist targeting dopamine D2 receptors and histamine H1 receptors. By blocking neurotransmitter binding and signal transduction within the chemoreceptor trigger zone of the central nervous system, the compound suppresses downstream emetic signaling pathways, thereby inhibiting the activation of reflexes that mediate nausea and vomiting responses.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
84 mg/mL
(197.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Tribenzagan Hydrochloride Solubility in DMSO
- Tribenzagan Hydrochloride Stock Solution
- Tribenzagan Hydrochloride Storage
- Tribenzagan Hydrochloride Stability
- Tribenzagan Hydrochloride Molecular Weight
- Tribenzagan Hydrochloride SMILES
- Tribenzagan Hydrochloride Chemical Structure (2D and 3D)
- Tribenzagan Hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.