CAS No. 77-93-0
Batch:
Purity:
Chemical Structure
Check the
Triethyl citrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 77-93-0 | |
|---|---|---|
| Molecular Formula |
C12H20O7 |
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| Molecular Weight (MW) | 276.28 | |
| SMILES | CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)O |
Triethyl citrate is a citric acid ester that functions as a plasticizer and pharmaceutical excipient. It increases polymer chain mobility and reduces glass transition temperatures in enteric and sustained-release film coatings, thereby modulating matrix permeability and drug release kinetics. Additionally, triethyl citrate serves as a competitive substrate for bacterial esterases, suppressing the enzymatic degradation of cutaneous lipids and preventing short-chain fatty acid generation. [1]
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.