CAS No. 101-20-2
Batch:
Purity:99.26
Chemical Structure
Check the
Triclocarban
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 101-20-2 | |
|---|---|---|
| Molecular Formula |
C13H9Cl3N2O |
|
| Molecular Weight (MW) | 315.58 | |
| SMILES | C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl |
Biological Activity
Triclocarban is an antibacterial agent commonly used in personal care products. It displays broad-spectrum antimicrobial activity and functions as an endocrine disruptor by modulating nuclear receptor signaling. Specifically, triclocarban enhances androgen receptor-dependent transcriptional activity in response to endogenous androgenic hormones. Downstream, this enhancement alters hormone-responsive gene expression, disrupts endocrine homeostasis, and modulates cellular proliferation in target tissues. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
63 mg/mL
(199.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.