CAS No. 99-14-9
Batch:
Purity:98.16
Chemical Structure
Check the
Tricarballylic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | propane-1,2,3-tricarboxylic acid | |
|---|---|---|
| CAS Number | 99-14-9 | |
| Molecular Formula |
C6H8O6 |
|
| Molecular Weight (MW) | 176.12 | |
| SMILES | C(C(CC(=O)O)C(=O)O)C(=O)O | |
| InChIKey | KQTIIICEAUMSDG-UHFFFAOYSA-N |
Tricarballylic acid is a metabolic inhibitor targeting aconitase that disrupts the citric acid cycle (Krebs cycle). By blocking aconitase activity, the compound interferes with tricarboxylic acid cycle flux and downstream mitochondrial energy metabolism. This inhibition leads to reduced cellular ATP production, altered metabolic homeostasis, and suppression of oxidative phosphorylation in affected biological systems. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(198.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.