CAS No. 593-56-6
Chemical Structure
Check the
TRC102 (methoxyamine hydrochloride)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 593-56-6 | |
|---|---|---|
| Molecular Formula |
CH5NO.ClH |
|
| Molecular Weight (MW) | 83.52 |
Biological Activity
TRC(methoxyamine) is a small-molecule inhibitor of the base excision repair (BER) pathway. It acts by covalently binding to reactive aldehyde groups within apurinic/apyrimidinic (AP) sites generated during DNA repair. This interaction disrupts AP site processing by BER enzymes, leading to the accumulation of toxic DNA single- and double-strand breaks that enhance chemotherapy-induced apoptosis in cancer cells. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Reference
Jump to
- TRC102 (methoxyamine hydrochloride) Clinical Trials
- TRC102 (methoxyamine hydrochloride) Solubility in DMSO
- TRC102 (methoxyamine hydrochloride) Stock Solution
- TRC102 (methoxyamine hydrochloride) Storage
- TRC102 (methoxyamine hydrochloride) Stability
- TRC102 (methoxyamine hydrochloride) Molecular Weight
- TRC102 (methoxyamine hydrochloride) Chemical Structure (2D and 3D)
- TRC102 (methoxyamine hydrochloride) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.