CAS No. 6402-36-4

Batch: Purity:99.94
Traumatic acid Chemical Structure
Chemical Structure
Check the Traumatic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6402-36-4
Molecular Formula

C12H20O4

Molecular Weight (MW) 228.28
SMILES C(CCCCC(=O)O)CCCC=CC(=O)O

Biological Activity

Traumatic acid (trans-2-dodecenedioic acid) is a naturally occurring plant hormone and potent wound-healing agent that acts as an intermediate in prostaglandin synthesis. It induces plant cell division at injury sites to promote rapid tissue repair and wound closure. Additionally, traumatic acid modulates oxidative stress responses and cellular metabolic pathways, driving cell proliferation and structural protein biosynthesis during tissue regeneration. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 46 mg/mL (201.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 23 mg/mL
Water ˂1 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

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Note: Technical data last updated: Sep 1, 2026.