CAS No. 1986-47-6

Batch: Purity:99.01
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Tranylcypromine HCl Chemical Structure
Chemical Structure
Check the Tranylcypromine HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1986-47-6
Molecular Formula

C9H12ClN
Molecular Weight (MW) 169.65
SMILES C1C(C1N)C2=CC=CC=C2.Cl

Ordering Information

Biological Activity

Tranylcypromine HCl is a monoamine oxidase inhibitor that also potently inhibits cytochrome P450 2A6 (CYP2A6). Inactivation of monoamine oxidase prevents the oxidative deamination of monoamine neurotransmitters, resulting in elevated levels of serotonin, norepinephrine, and dopamine. Furthermore, inhibition of CYP2A6 disrupts hepatic nicotine and xenobiotic metabolism pathways, modulating downstream enzymatic oxidation and central nervous system signaling pathways involved in neurological regulation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 34 mg/mL (200.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 34 mg/mL
Ethanol 34 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.