CAS No. 1400591-39-0

Batch: Purity:99.58
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Tosufloxacin p-Toluenesulfonate Hydrate Chemical Structure
Chemical Structure
Check the Tosufloxacin p-Toluenesulfonate Hydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1400591-39-0
Molecular Formula

C19H15F3N4O3.C7H8O3S.H2O
Molecular Weight (MW) 594.56
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F.O

Ordering Information

Biological Activity

Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV. By inhibiting these essential enzymes, tosufloxacin impairs bacterial DNA replication, transcription, and repair pathways, triggering double-stranded DNA breaks and bactericidal activity. The compound exhibits broad-spectrum antibacterial activity against various Gram-positive and Gram-negative pathogens, preventing bacterial growth and cell division. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (168.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.