Torin 1 SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

Product Name: Torin 1
Catalog Number: S2827
CAS Number: 1222998-36-8
IUPAC Name: Benzo[h]-1,6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-

Relevant identified uses and uses advised against

Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

Company : Selleck Chemicals
TollFree : +1 877 796-6397
Tel : +1 832 582-8158
Fax : +1 832 582-8590

Emergency telephone number

Emergency phone #: +1 832 582-8158

2. HAZARDS IDENTIFICATION

GHS Classification:
Not a hazardous substance or mixture in accordance with the OSHA Hazard Communication Standard (29 CFR 1910.1200).

GHS Label Elements:
No hazard pictogram, signal word, hazard statement(s), or precautionary statement(s) are required.

Other Hazards:
None known.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Substance/Mixture: Substance

Substance Name: Benzo[h]-1,6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-

Components:
No hazardous ingredients are present in this substance.

4. FIRST AID MEASURES

Inhalation: If inhaled, move the person to fresh air.
Skin Contact: Take off all contaminated clothing immediately. Rinse the skin with water or shower.
Eye Contact: Rinse out with plenty of water. Remove contact lenses if present.
Ingestion: After swallowing, have the victim drink water (maximum of two glasses). Consult a physician if the individual feels unwell.
Most Important Symptoms and Effects: The most important known symptoms and effects are described in the hazard identification (Section 2) and toxicological information (Section 11).
Protection of First-Aiders: Refer to Section 8 for personal protection.
Notes to Physician: N/A.

5. FIREFIGHTING MEASURES

Suitable Extinguishing Media: Water, foam, carbon dioxide (CO2), or dry powder.
Unsuitable Extinguishing Media: No limitations of extinguishing agents are given for this substance.
Specific Hazards: The material is combustible. Development of hazardous combustion gases or vapors is possible in the event of a fire.
Hazardous Combustion Products: Nature of decomposition products is not known.
Specific Extinguishing Methods: N/A.
Further Information: Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special Protective Equipment for Firefighters: In the event of fire, wear self-contained breathing apparatus.

6. ACCIDENTAL RELEASE MEASURES

Personal Precautions and Emergency Procedures:

For non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, and consult an expert.
For emergency responders: Refer to personal protection in Section 8.

Environmental Precautions: Do not let the product enter drains.

Methods and Materials for Containment and Cleaning Up: Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see Sections 7 and 10). Take up dry and dispose of properly. Clean up the affected area and avoid the generation of dusts.

7. HANDLING AND STORAGE

Precautions for Safe Handling: Refer to Section 2.2 for precautions.
Conditions for Safe Storage: Keep the container tightly closed and in a dry place.
Storage Class: 11, Combustible Solids.
Recommended Storage Temperature: Refer to the product label for the recommended storage temperature.
Storage Stability: Refer to the product label for storage stability information.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Exposure Limits: Contains no substances with occupational exposure limit values.
Engineering Measures: N/A.

Personal Protective Equipment:

Respiratory Protection: Required when dusts are generated. Recommended filter type: P1. Respiratory protection must comply with DIN EN 143, DIN 14387, or other relevant standards.
Hand Protection: Handle with nitrile rubber gloves.
- Full contact: Glove thickness 0.11 mm; Break through time 480 min (e.g., KCL 741 Dermatril-L).
- Splash contact: Glove thickness 0.11 mm; Break through time 480 min (e.g., KCL 741 Dermatril-L).
Eye Protection: Use safety glasses tested and approved under appropriate government standards such as NIOSH (US) or EN 166 (EU).
Hygiene Measures: Change contaminated clothing. Wash hands after working with the substance.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: powder
Color: yellow to white
Odor: N/A
Odor Threshold: N/A
pH: N/A
Melting Point: N/A
Boiling Point: N/A
Flash Point: Not applicable
Evaporation Rate: N/A
Flammability (solid, gas): N/A
Flammability (liquids): N/A
Burning Rate: N/A
Upper/Lower Explosion Limit: N/A
Vapor Pressure: N/A
Relative Vapor Density: N/A
Relative Density: N/A
Density: 1.362 g/cm3 (at 68 degrees F / 20 degrees C, 1,013 hPa)
Water Solubility: N/A
Partition Coefficient (n-octanol/water): N/A
Autoignition Temperature: N/A
Decomposition Temperature: N/A
Viscosity: N/A
Explosive Properties: Not classified as explosive.
Oxidizing Properties: None
Molecular Weight: 607.62 g/mol
Particle Size: N/A

10. STABILITY AND REACTIVITY

Reactivity: Flammable organic substances in fine distribution may generally have a dust explosion potential when whirled up.
Chemical Stability: The product is chemically stable under standard ambient conditions (room temperature).
Possibility of Hazardous Reactions: N/A.
Conditions to Avoid: No information available.
Incompatible Materials: N/A.
Hazardous Decomposition Products: In the event of fire, refer to Section 5.

11. TOXICOLOGICAL INFORMATION

Acute Toxicity:

Oral: N/A.
Inhalation: N/A.
Dermal: N/A.

Skin Corrosion/Irritation: N/A.
Serious Eye Damage/Eye Irritation: N/A.
Respiratory or Skin Sensitization: N/A.
Germ Cell Mutagenicity: N/A.

Carcinogenicity:

IARC: No component present at levels greater than or equal to 0.1% is identified as a probable, possible, or confirmed human carcinogen.
NTP: No component present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen.
OSHA: No component present at levels greater than or equal to 0.1% is on OSHA-s list of regulated carcinogens.

Reproductive Toxicity: N/A.
STOT - Single Exposure: N/A.
STOT - Repeated Exposure: N/A.
Aspiration Hazard: N/A.
Additional Information: N/A.

12. ECOLOGICAL INFORMATION

Ecotoxicity: N/A.
Persistence and Degradability: N/A.
Bioaccumulative Potential: N/A.
Mobility in Soil: N/A.

Other Adverse Effects:

Ozone-Depletion Potential: This product neither contains nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App. A + B).

13. DISPOSAL CONSIDERATIONS

Waste Treatment Methods: Waste material must be disposed of in accordance with national and local regulations. Leave chemicals in their original containers. Do not mix with other waste. Handle uncleaned containers in the same manner as the product itself.

14. TRANSPORT INFORMATION

DOT (49 CFR): Not regulated as a dangerous good.
IATA: Not regulated as a dangerous good.
IMDG: Not regulated as a dangerous good.
Transport in Bulk: Not applicable for the product as supplied.
Poison Inhalation Hazard: No.
Special Precautions for User: Not classified as dangerous in the meaning of transport regulations.

15. REGULATORY INFORMATION

CERCLA Reportable Quantity
This material does not contain any components with a CERCLA RQ.

SARA 304 Extremely Hazardous Substances Reportable Quantity
This material does not contain any components with a section 304 EHS RQ.

SARA 302 Extremely Hazardous Substances Threshold Planning Quantity
This material does not contain any components with a section 302 EHS TPQ.

SARA 313 : This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

Clean Air Act
This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).
This product does not contain any hazardous air pollutants (HAP), as defined by the U.S. Clean Air Act Section 112 (40 CFR 61).
This product does not contain any chemicals listed under the U.S. Clean Air Act Section 112(r) for Accidental Release Prevention (40 CFR 68.130, Subpart F).
This product does not contain any chemicals listed under the U.S. Clean Air Act Section 111 SOCMI Intermediate or Final VOC's (40 CFR 60.489).

Clean Water Act
This product does not contain any Hazardous Substances listed under the U.S. CleanWater Act, Section 311, Table 116.4A.
This product does not contain any Hazardous Chemicals listed under the U.S. CleanWater Act, Section 311, Table 117.3.
This product does not contain any toxic pollutants listed under the U.S. Clean Water Act Section 307
This product does not contain any priority pollutants related to the U.S. Clean Water Act

US State Regulations
Massachusetts Right To Know
No components are subject to the Massachusetts Right to Know Act.
Maine Chemicals of High Concern
Product does not contain any listed chemicals
Vermont Chemicals of High Concern
Product does not contain any listed chemicals
Washington Chemicals of High Concern
Product does not contain any listed chemicals

The components of this product are reported in the following inventories:
TSCA : Product contains substance(s) not listed on TSCA inventory.

TSCA list
No substances are subject to a Significant New Use Rule.
No substances are subject to TSCA 12(b) export notification requirements.

16. OTHER INFORMATION

Revision Date: 2026/07/31
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.