SMILES:
CCC1=CC=C(C=C1)CC2=CC3=C(COC34C(C(C(C(O4)CO)O)O)O)C=C2.O
Chemical Structure
Check the
Tofogliflozin(CSG 452)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol;hydrate | |
|---|---|---|
| CAS Number | 1201913-82-7 | |
| Molecular Formula |
C22H26O6.H2O |
|
| Molecular Weight (MW) | 404.45 | |
| SMILES | CCC1=CC=C(C=C1)CC2=CC3=C(COC34C(C(C(C(O4)CO)O)O)O)C=C2.O | |
| InChIKey | ZXOCGDDVNPDRIW-NHFZGCSJSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
84 mg/mL
(207.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 84 mg/mL |
| Water | 4 mg/mL |
| DMSO |
80 mg/mL
(197.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 80 mg/mL |
| Water | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Tofogliflozin(CSG 452) Clinical Trials
- Tofogliflozin(CSG 452) Solubility in DMSO
- Tofogliflozin(CSG 452) Stock Solution
- Tofogliflozin(CSG 452) Storage
- Tofogliflozin(CSG 452) Stability
- Tofogliflozin(CSG 452) Molecular Weight
- Tofogliflozin(CSG 452) CAS Number
- Tofogliflozin(CSG 452) Chemical Structure (2D and 3D)
- Tofogliflozin(CSG 452) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.