CAS No. 144796-71-4

TNF-α (31-45), human Chemical Structure
Chemical Structure
Check the TNF-α (31-45), human product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]butanedioic acid
CAS Number 144796-71-4
Molecular Formula

C69H122N26O22
Molecular Weight (MW) 1667.87
InChIKey HYFATHUJEOQTRM-PJKQPBPGSA-N

Biological Activity

TNF-α (31-45), human is a synthetic peptide fragment of human tumor necrosis factor-alpha that acts as an activator of the NF-kB signaling pathway. Derived from an inflammatory cytokine produced by macrophages and monocytes, it initiates downstream signaling events associated with acute inflammation. Activation of these intracellular pathways regulates essential cellular processes, including necrosis and apoptosis, serving as a functional model for autoimmune disease research. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Reference

[1] Hayden MS, et al. Genes Dev. 2004;18(18):2195-224.

Jump to

Note: Technical data last updated: Sep 1, 2026.