CAS No. 444-27-9

Batch: Purity:99.78
Timonacic Chemical Structure
Chemical Structure
Check the Timonacic product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 444-27-9
Molecular Formula

C4H7NO2S

Molecular Weight (MW) 133.17
SMILES C1C(NCS1)C(=O)O

Ordering Information

Biological Activity

Timonacic (Thiazolidine-4-carboxylic acid) is a cyclic sulfur amino acid derivative that functions as an antioxidant and potential antineoplastic agent. It acts as an intracellular thiol donor and free radical scavenger, modulating cellular oxidative stress pathways. By enhancing antioxidant defense mechanisms and restoring cellular redox balance, timonacic suppresses oxidative cellular damage and inhibits transformed cell phenotypes.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 27 mg/mL
DMSO 1 mg/mL (7.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.