CAS No. 328898-40-4

Batch: Purity:99.9
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Tildipirosin Chemical Structure
Chemical Structure
Check the Tildipirosin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 328898-40-4
Molecular Formula

C41H71N3O8
Molecular Weight (MW) 734.02
SMILES CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CCCCC3)C)C)CN4CCCCC4

Biological Activity

Tildipirosin is a semi-synthetic, 16-membered tribasic macrolide antibiotic that selectively targets bacterial protein synthesis through binding to the 50S ribosomal subunit. By blocking nascent peptide chain elongation, it disrupts essential bacterial translation pathways and inhibits overall cell growth. Consequently, this compound effectively suppresses bacterial proliferation and viability across susceptible respiratory tract pathogens.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (136.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.