CAS No. 55142-85-3
Batch:
Purity:
Chemical Structure
Check the
Ticlopidine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine | |
|---|---|---|
| CAS Number | 55142-85-3 | |
| Molecular Formula |
C14H14ClNS |
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| Molecular Weight (MW) | 263.79 | |
| SMILES | C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl | |
| InChIKey | PHWBOXQYWZNQIN-UHFFFAOYSA-N |
Ticlopidine is an orally active inhibitor of adenosine diphosphate (ADP)-induced platelet aggregation and a potent inhibitor of cytochrome P450 2B6 (CYP2B6). By antagonizing ADP-mediated signaling through platelet P2Y12 receptors, ticlopidine inhibits ADP-stimulated activation of the glycoprotein IIb/IIIa complex. This interference suppresses downstream platelet granule release and fibrinogen binding, ultimately inhibiting platelet aggregation and vascular thrombus formation. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
20 mg/mL
(75.81 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.