CAS No. 33430-62-5

Batch: Purity:99.94
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Thymidine 5'-monophosphate disodium salt Chemical Structure
Chemical Structure
Check the Thymidine 5'-monophosphate disodium salt product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 33430-62-5
Molecular Formula

C10H13N2Na2O8P
Molecular Weight (MW) 366.17
SMILES [Na+].[Na+].CC1=CN(C2CC(O)C(CO[P]([O-])([O-])=O)O2)C(=O)NC1=O

Ordering Information

Biological Activity

Thymidine 5'-monophosphate disodium salt is an endogenous pyrimidine nucleotide metabolite that serves as an essential precursor in the DNA synthesis pathway. Formed by the phosphorylation of thymidine or via thymidylate synthase-mediated conversion of deoxyuridine monophosphate, it is further phosphorylated to dTTP to support DNA replication and genomic repair processes. Intracellular dTMP pools directly influence cell proliferation, cell cycle progression, and nucleic acid metabolic homeostasis.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 73 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.