CAS No. 273724-21-3

Batch: Purity:99.92
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Thiamine monophosphate chloride dihydrate Chemical Structure
Chemical Structure
Check the Thiamine monophosphate chloride dihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 273724-21-3
Molecular Formula

C12H22ClN4O6PS
Molecular Weight (MW) 416.82
SMILES O.O.[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO[P](O)(O)=O)C(=N1)N

Ordering Information

Biological Activity

Thiamine monophosphate chloride dihydrate is an endogenous metabolite that serves as a key intermediate in vitamin B1 processing and thiamine metabolism pathways. It functions within cellular thiamine homeostasis, playing a vital role in carbohydrate processing and mitochondrial energy production pathways. Hydrolysis or kinase-mediated conversion of thiamine monophosphate generates active coenzymes like thiamine pyrophosphate, supporting cellular respiration and central metabolic phenotypes. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 83 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.