CAS No. 84-22-0
Batch:
Purity:99
Chemical Structure
Check the
Tetryzoline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 84-22-0 | |
|---|---|---|
| Molecular Formula |
C13H16N2 |
|
| Molecular Weight (MW) | 200.28 | |
| SMILES | C1CC(C2=CC=CC=C2C1)C3=NCCN3 |
Tetryzoline (Tetrahydrozoline) is an imidazoline-derived alpha-adrenergic receptor agonist that selectively stimulates alpha-1 and alpha-2 adrenoceptors. Activation of alpha-adrenergic signaling induces vascular smooth muscle contraction, leading to local vasoconstriction and reduced mucosal congestion and hyperemia. This vascular response mediates downstream reduction of edema and redness in affected ocular and nasal tissue beds. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.