CAS No. 23434-88-0

Batch: Purity:99.77
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Tetrahydropiperine Chemical Structure
Chemical Structure
Check the Tetrahydropiperine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 23434-88-0
Molecular Formula

C17H23NO3
Molecular Weight (MW) 289.37
SMILES C1CCN(CC1)C(=O)CCCCC2=CC3=C(C=C2)OCO3

Ordering Information

Biological Activity

Tetrahydropiperine, an alkaloid derivative of piperine, is an active compound with anticonvulsant, analgesic, and skin penetration-enhancing activities. It influences neural ion channel signaling and central nervous system pathways to reduce seizure susceptibility and attenuate pain responses. In addition to its neuroprotective and analgesic effects, tetrahydropiperine displays insecticidal properties by interfering with vital physiological pathways in target insect species. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 58 mg/mL (200.43 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 58 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.