CAS No. 165538-40-9
Batch:
Purity:98.54
Chemical Structure
Check the
Terutroban
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 165538-40-9 | |
|---|---|---|
| Molecular Formula |
C20H22ClNO4S |
|
| Molecular Weight (MW) | 407.91 |
Terutroban (S-18886) is a potent and selective antagonist of the thromboxane A2 prostanoid (TP) receptor. By blocking TP receptor activation, it inhibits thromboxane-mediated platelet aggregation, vascular smooth muscle contraction, and vascular endothelial inflammation. These cellular responses suppress downstream pro-thrombotic and pro-inflammatory signaling, exhibiting antithrombotic, antivasoconstricting, and antiatherosclerotic phenotypes in preclinical models of vascular disease. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
82 mg/mL
(201.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.