CAS No. 67915-31-5
Batch:
Purity:99.96
Chemical Structure
Check the
Terconazole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-propan-2-ylpiperazine | |
|---|---|---|
| CAS Number | 67915-31-5 | |
| Molecular Formula |
C26H31Cl2N5O3 |
|
| Molecular Weight (MW) | 532.46 | |
| SMILES | CC(C)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl | |
| InChIKey | BLSQLHNBWJLIBQ-OZXSUGGESA-N |
Terconazole is a broad-spectrum triazole antifungal agent that targets fungal lanosterol 14α-demethylase. By inhibiting lanosterol 14α-demethylase, terconazole disrupts ergosterol biosynthesis, compromising fungal cell membrane integrity and permeability. This pathway inhibition impairs cell membrane stability and results in cellular lysis and cell death, exhibiting broad-spectrum activity against pathogenic fungi including Candida albicans. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 100 mg/mL |
| DMSO |
49 mg/mL
(92.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.