CAS No. 113712-98-4

Batch: Purity:99.96
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Tenatoprazole Chemical Structure
Chemical Structure
Check the Tenatoprazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine
CAS Number 113712-98-4
Molecular Formula

C16H18N4O3S
Molecular Weight (MW) 346.4
SMILES CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC
InChIKey ZBFDAUIVDSSISP-UHFFFAOYSA-N

Ordering Information

Biological Activity

Tenatoprazole is a prodrug proton pump inhibitor (PPI) that inhibits gastric H(+),K(+)-ATPase-mediated proton transport with an IC50 of. It covalently binds and selectively labels the gastric H(+),K(+)-ATPase alpha-subunit at approximately 2.6 nM/mg of protein. By inhibiting the enzymatic activity of the gastric proton pump, tenatoprazole disrupts gastric acid secretion and promotes sustained suppression of gastric acid production. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 69 mg/mL (199.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 11 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.