CAS No. 191729-45-0
Batch:
Purity:99.76
Chemical Structure
Check the
Tenacissoside H
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 191729-45-0 | |
|---|---|---|
| Molecular Formula |
C42H66O14 |
|
| Molecular Weight (MW) | 794.97 | |
| SMILES | CCC(C)C(=O)OC1C2C3(CCC(CC3CCC24C5(O4)CCC(C5(C1OC(=O)C)C)C(=O)C)OC6CC(C(C(O6)C)OC7C(C(C(C(O7)C)O)OC)O)OC)C |
Biological Activity
Tenacissoside H is a natural C21 steroidal glycoside isolated from Marsdenia tenacissima that exerts anti-inflammatory and anti-tumor activities. It inhibits cancer cell proliferation and promotes apoptosis by modulating downstream signaling pathways and reversing multidrug resistance mechanisms. Additionally, Tenacissoside H suppresses pro-inflammatory mediator expression, attenuating inflammatory responses and tumor progression across preclinical models. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(125.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.