CAS No. 1359993-59-1

Batch: Purity:99.25
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Telratolimod (3M-052) Chemical Structure
Chemical Structure
Check the Telratolimod (3M-052) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-[4-(4-amino-2-butylimidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide
CAS Number 1359993-59-1
Molecular Formula
C36H59N5O2
Molecular Weight (MW) 593.89
SMILES CCCCCCCCCCCCCCCCCC(=O)NCCCCON1C(=NC2=C1C3=CC=CC=C3N=C2N)CCCC
InChIKey RRTPWQXEERTRRK-UHFFFAOYSA-N

Ordering Information

Biological Activity

Telratolimod (3M-052) is a potent agonist of toll-like receptor 7 (TLR7) and toll-like receptor 8 (TLR8). Activation of TLR7/8 signaling triggers NF-κB pathway activation, stimulating the secretion of type I interferons and pro-inflammatory cytokines. This cascade promotes dendritic cell maturation, enhances antigen presentation, and boosts cytotoxic T-lymphocyte responses, culminating in potent antitumor immune activity. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Ethanol 13 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.